$INSM

Top Institutions

1

Artisan Partners

6,527,301 shares

1.71%

% of Portfolio

2

David E. Shaw - D.E. Shaw & Co.

5,625,825 shares

0.55%

% of Portfolio

3

Adage Capital Partners

900,000 shares

0.23%

% of Portfolio

4

Capital International Investors

5,595,194 shares

0.21%

% of Portfolio

5

Ensign Peak Advisors

499,756 shares

0.15%

% of Portfolio

6

Fidelity International (FIL)

828,947 shares

0.11%

% of Portfolio

7

Franklin Resources

2,617,251 shares

0.10%

% of Portfolio

8

Israel Englander - Millennium Management

1,157,786 shares

0.08%

% of Portfolio

9

Ken Griffin - Citadel Advisors

2,182,571 shares

0.06%

% of Portfolio

10

Larry Fink - BlackRock

16,678,146 shares

0.05%

% of Portfolio

11

Geode Capital Management

4,450,389 shares

0.05%

% of Portfolio

12

Invesco

1,988,968 shares

0.05%

% of Portfolio

13

Cliff Asness - AQR Capital Management

675,485 shares

0.05%

% of Portfolio

14

BNP Paribas

604,600 shares

0.05%

% of Portfolio

15

Dmitry Balyasny - Balyasny Asset Management

221,707 shares

0.05%

% of Portfolio

16

Jennison Associates

604,694 shares

0.07%

% of Portfolio

17

T. Rowe Price

3,092,807 shares

0.06%

% of Portfolio

18

UBS Group

1,737,481 shares

0.04%

% of Portfolio

19

AllianceBernstein (AB)

688,734 shares

0.04%

% of Portfolio

20

Voya Investment Mgmt

243,706 shares

0.04%

% of Portfolio

21

State Street Corp

5,551,699 shares

0.03%

% of Portfolio

22

Northern Trust Corp

1,294,000 shares

0.03%

% of Portfolio

23

Charles Schwab

1,069,390 shares

0.03%

% of Portfolio

24

Legal & General

787,079 shares

0.03%

% of Portfolio

25

Janus Henderson Group

419,304 shares

0.03%

% of Portfolio

26

CalPERS

344,612 shares

0.03%

% of Portfolio

27

Neuberger Berman

270,700 shares

0.03%

% of Portfolio

28

Two Sigma Investments

237,017 shares

0.03%

% of Portfolio

29

David Solomon - Goldman Sachs

942,646 shares

0.02%

% of Portfolio

30

Nuveen

534,750 shares

0.02%

% of Portfolio

31

SG Americas Securities

137,149 shares

0.02%

% of Portfolio

32

Morgan Stanley

1,331,542 shares

0.01%

% of Portfolio

33

Capital World Investors

1,362,291 shares

0.03%

% of Portfolio

34

Mitsubishi Ufj Asset Management Co., Ltd.

255,247 shares

0.03%

% of Portfolio

35

Wellington Management

399,044 shares

0.01%

% of Portfolio

36

Jan van Eck - VanEck

104,290 shares

0.01%

% of Portfolio

37

Renaissance Technologies

20,300 shares

0.01%

% of Portfolio

38

Mike Hankin - Brown Advisory INC

22,949 shares

0.01%

% of Portfolio

39

Robeco Institutional Asset Management

20,774 shares

NaN%

% of Portfolio

40

Canada Pension Plan Investment Board

39,900 shares

NaN%

% of Portfolio

41

Jane Street Group

11,401 shares

NaN%

% of Portfolio

42

PNC Financial Services

8,910 shares

NaN%

% of Portfolio

43

Exoduspoint Capital Management, Lp

148,133 shares

0.20%

% of Portfolio

44

Ray Dalio - Bridgewater Associates

295,579 shares

0.22%

% of Portfolio

45

Lord, Abbett & Co. LLC

397,261 shares

0.21%

% of Portfolio

46

Garrett Thornburg - Thornburg Invest Mgmt

38,337 shares

0.07%

% of Portfolio

47

John P. Calamos, Sr. - Calamos Advisors LLC