$PCRX

Renaissance Technologies

1,825,501 shares

David E. Shaw - D.E. Shaw & Co.

1,982,724 shares

Ken Griffin - Citadel Advisors

797,281 shares

Two Sigma Investments

526,851 shares

Josef Lakonishok - Lsv Asset Management

517,100 shares

Robeco Institutional Asset Management

158,096 shares

Dmitry Balyasny - Balyasny Asset Management

106,418 shares

David Solomon - Goldman Sachs

1,569,916 shares

Jane Street Group

140,247 shares

Larry Fink - BlackRock

6,735,343 shares

Charles Schwab

732,042 shares

UBS Group

562,040 shares

Wellington Management

478,383 shares

Morgan Stanley

1,392,548 shares

Geode Capital Management

1,143,820 shares

Cliff Asness - AQR Capital Management

154,298 shares

Northern Trust Corp

519,412 shares

State Street Corp

1,919,610 shares

Lazard Asset Management

39,470 shares

Israel Englander - Millennium Management

57,031 shares

Invesco

237,580 shares

Voya Investment Mgmt

28,506 shares

SG Americas Securities

24,303 shares

Nuveen

89,806 shares

Legal & General

95,968 shares

AllianceBernstein (AB)

52,993 shares

BNP Paribas

17,351 shares

Janus Henderson Group

23,319 shares

Ensign Peak Advisors

4,870 shares

Franklin Resources

32,922 shares

T. Rowe Price

53,977 shares

PNC Financial Services

3,751 shares

Mitsubishi Ufj Asset Management Co., Ltd.

172 shares

Canada Pension Plan Investment Board

0 shares

Jefferies Group

196,292 shares

PSP Investments

147,040 shares

Verition Fund Management LLC

29,919 shares

Natixis

34,000 shares

Joel Greenblatt - Gotham Asset Management

44,939 shares

New York State Teachers Retirement System

14,027 shares

Paul Tudor Jones - Tudor Investment Corp

0 shares

Segall Bryant & Hamill, LLC

0 shares

Jamie Dimon - JPMorgan Chase

0 shares

John Hussman - Hussman Strategic Advisors

0 shares