$INSM

Artisan Partners

6,527,301 股

David E. Shaw - D.E. Shaw & Co.

5,625,825 股

Adage Capital Partners

900,000 股

Capital International Investors

5,595,194 股

Ensign Peak Advisors

499,756 股

Fidelity International (FIL)

828,947 股

Franklin Resources

2,617,251 股

Israel Englander - Millennium Management

1,157,786 股

Ken Griffin - Citadel Advisors

2,182,571 股

Larry Fink - BlackRock

16,678,146 股

Geode Capital Management

4,450,389 股

Invesco

1,988,968 股

Cliff Asness - AQR Capital Management

675,485 股

BNP Paribas

604,600 股

Dmitry Balyasny - Balyasny Asset Management

221,707 股

Jennison Associates

604,694 股

T. Rowe Price

3,092,807 股

UBS Group

1,737,481 股

AllianceBernstein (AB)

688,734 股

Voya Investment Mgmt

243,706 股

State Street Corp

5,551,699 股

Northern Trust Corp

1,294,000 股

Charles Schwab

1,069,390 股

Legal & General

787,079 股

Janus Henderson Group

419,304 股

CalPERS

344,612 股

Neuberger Berman

270,700 股

Two Sigma Investments

237,017 股

David Solomon - Goldman Sachs

942,646 股

Nuveen

534,750 股

SG Americas Securities

137,149 股

Morgan Stanley

1,331,542 股

Capital World Investors

1,362,291 股

Mitsubishi Ufj Asset Management Co., Ltd.

255,247 股

Wellington Management

399,044 股

Jan van Eck - VanEck

104,290 股

Renaissance Technologies

20,300 股

Mike Hankin - Brown Advisory INC

22,949 股

Robeco Institutional Asset Management

20,774 股

Canada Pension Plan Investment Board

39,900 股

Jane Street Group

11,401 股

PNC Financial Services

8,910 股

Exoduspoint Capital Management, Lp

148,133 股

Ray Dalio - Bridgewater Associates

295,579 股

Lord, Abbett & Co. LLC

397,261 股

Garrett Thornburg - Thornburg Invest Mgmt

38,337 股

John P. Calamos, Sr. - Calamos Advisors LLC

36,373 股

Nomura Holdings INC

19,045 股

PFA Pension

114,788 股

WCM Investment Management

15,707 股