$VRTX

Capital World Investors

26,115,014 股

Franklin Resources

3,347,253 股

Invesco

8,043,052 股

Wellington Management

3,247,658 股

Adage Capital Partners

393,964 股

Voya Investment Mgmt

505,219 股

Jennison Associates

2,998,530 股

Capital International Investors

4,695,144 股

Robeco Institutional Asset Management

404,396 股

Amundi

1,546,509 股

Legal & General

1,870,015 股

New York State Teachers Retirement System - New York State Teachers Retirement System

206,935 股

Jamie Dimon - JPMorgan Chase

6,517,600 股

Larry Fink - BlackRock

24,109,373 股

Mitsubishi Ufj Asset Management Co., Ltd.

647,193 股

Neuberger Berman

559,445 股

Ensign Peak Advisors

210,483 股

State Street Corp

11,871,459 股

Geode Capital Management

6,017,848 股

SG Americas Securities

523,720 股

Northern Trust Corp

2,486,478 股

CalPERS

447,499 股

Charles Schwab

2,041,282 股

Nuveen

1,081,685 股

Cliff Asness - AQR Capital Management

616,170 股

David Solomon - Goldman Sachs

2,481,761 股

Two Sigma Investments

285,000 股

Canada Pension Plan Investment Board

355,082 股

Dmitry Balyasny - Balyasny Asset Management

145,005 股

Morgan Stanley

3,242,139 股

T. Rowe Price

1,728,421 股

Israel Englander - Millennium Management

468,410 股

BNP Paribas

262,258 股

PSP Investments

41,334 股

UBS Group

712,259 股

WCM Investment Management

1,152,094 股

PFA Pension

93,959 股

Lazard Asset Management

93,287 股

Jan van Eck - VanEck

143,881 股

Ken Griffin - Citadel Advisors

510,430 股

Baillie Gifford

272,561 股

Joel Greenblatt - Gotham Asset Management

18,986 股

PNC Financial Services

69,358 股

Fidelity International (FIL)

26,508 股

Mike Hankin - Brown Advisory INC

7,562 股

Ken Fisher - Fisher Asset Management

24,478 股

Jane Street Group

11,231 股

Steve Cohen - Point72 Asset Management

2,625 股

David E. Shaw - D.E. Shaw & Co.

3,105 股

Renaissance Technologies

320,008 股