$VRTX

Capital World Investors

25,368,124 股

AllianceBernstein (AB)

3,910,786 股

Janus Henderson Group

2,131,527 股

Renaissance Technologies

421,688 股

Wellington Management

3,212,589 股

Voya Investment Mgmt

527,047 股

Legal & General

1,955,764 股

Jennison Associates

2,740,059 股

Capital International Investors

5,126,077 股

Robeco Institutional Asset Management

401,644 股

Larry Fink - BlackRock

23,969,517 股

Neuberger Berman

551,522 股

State Street Corp

11,730,139 股

Invesco

2,561,057 股

Mitsubishi Ufj Asset Management Co., Ltd.

597,497 股

Ensign Peak Advisors

215,165 股

Geode Capital Management

6,139,621 股

Adage Capital Partners

251,990 股

Lazard Asset Management

213,131 股

Northern Trust Corp

2,564,264 股

CalPERS

503,374 股

Two Sigma Investments

378,146 股

Charles Schwab

1,920,871 股

Nuveen

1,084,495 股

David Solomon - Goldman Sachs

2,417,875 股

Morgan Stanley

3,188,881 股

T. Rowe Price

1,760,122 股

BNP Paribas

415,625 股

David E. Shaw - D.E. Shaw & Co.

248,960 股

Franklin Resources

551,132 股

Canada Pension Plan Investment Board

190,051 股

Jan van Eck - VanEck

146,116 股

UBS Group

630,618 股

Cliff Asness - AQR Capital Management

171,031 股

SG Americas Securities

56,982 股

Ken Griffin - Citadel Advisors

339,298 股

Dmitry Balyasny - Balyasny Asset Management

40,137 股

Israel Englander - Millennium Management

30,823 股

Jane Street Group

122,946 股

Baillie Gifford

199,421 股

PNC Financial Services

71,942 股

Fidelity International (FIL)

21,623 股

Mike Hankin - Brown Advisory INC

7,653 股

Ken Fisher - Fisher Asset Management

31,158 股

Manning & Napier

220,589 股

Lord, Abbett & Co. LLC

166,509 股

Segall Bryant & Hamill, LLC

29,994 股

New York State Teachers Retirement System

211,336 股

PFA Pension

134,996 股

New York Life Invest

38,069 股